For the past 3 weeks or so, my car has been making a noticeable intermittent pulsing hissing sound from what sounds like the front passenger wheel well area. I have no engine codes. Turning off the A/C does not make the noise go away. The hissing noise seems to cycle on and off will last for about 30 seconds then go away for a bit then return.

I don't have access to a lift, but its sounds like it is coming from a an area towards the bottom front passenger side of the engine. I'm not losing any oil or coolant. The pulsing sound of the hissing increases with the engine rpms. The noise seems to be audible only about 10% of the time the engine is running which makes the exact location of the sound hard to pin down, as I've only been able to pull over and try to search for the sound while it was audible once.

What could this be?

Anyone?

If it's coming from the FR bottom part of an engine than it sounds like an alternator bearings.
Try to load an alternator (turn on every possible heaters, hi beams, max. vents) and see if the sound gets louder.

Remove the belt and run it off battery for a minute. First check the radiator hoses.

The vacuum reservoirs are in that area, they look like 2 coke cans. Might be a leaking hose.

I would agree with fredd60, suspect the vacuum reservoir. If the sound responds instantly to accelerator and for a few secs after switching off then look with avengance in that area.